1.02010-04-08 22:04:50 UTC2019-11-26 02:55:55 UTCFDB001108(S)-[6]-GingerolConstituent of ginger Zingiber officinale. (S)-[6]-Gingerol is found in many foods, some of which are caraway, star anise, cumin, and ginger.(+)-[6]-Gingerol(5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one(S)-(+)-[6]-Gingerol(S)-(+)-[6]Gingerol(S)-6-Gingerol[6]-Gingerol3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-5-Hydroxy-1-(4-hydroxy-3-methoxtphenyl)-3-decanone5-Hydroxy-1-(4-hydroxy-3-methoxycyclohexyl)decan-3-one5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone6-GingerolGingerolC17H26O4294.3859294.183109325-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-onegingerol58253-27-3CCCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1InChI=1S/C17H26O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h8,10-11,14,18,20H,3-7,9,12H2,1-2H3NLDDIKRKFXEWBK-UHFFFAOYSA-N belongs to the class of organic compounds known as gingerols. Gingerols are compounds containing a gingerol moiety, which is structurally characterized by a 4-hydroxy-3-methoxyphenyl group substituted at the C6 carbon atom by a 5-hydroxy-alkane-3-one.GingerolsOrganic compoundsBenzenoidsPhenolsMethoxyphenolsAromatic homomonocyclic compounds1-hydroxy-2-unsubstituted benzenoidsAlkyl aryl ethersAnisolesBeta-hydroxy ketonesFatty alcoholsHydrocarbon derivativesMethoxybenzenesOrganic oxidesPhenoxy compoundsSecondary alcohols1-hydroxy-2-unsubstituted benzenoidAlcoholAlkyl aryl etherAnisoleAromatic homomonocyclic compoundBeta-hydroxy ketoneCarbonyl groupEtherFatty acylFatty alcoholGingerolHydrocarbon derivativeKetoneMethoxybenzeneMonocyclic benzene moietyOrganic oxideOrganic oxygen compoundOrganooxygen compoundPhenol etherPhenoxy compoundSecondary alcohola phenylpropanoidSolidlogp3.45logs-3.57solubility7.96e-02 g/lmelting_point31 oClogp3.62pka_strongest_acidic9.95pka_strongest_basic-2.8iupac5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-oneaverage_mass294.3859mono_mass294.18310932smilesCCCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1formulaC17H26O4inchiInChI=1S/C17H26O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h8,10-11,14,18,20H,3-7,9,12H2,1-2H3inchikeyNLDDIKRKFXEWBK-UHFFFAOYSA-Npolar_surface_area66.76refractivity83.11polarizability33.76rotatable_bond_count10acceptor_count4donor_count2physiological_charge0formal_charge0Specdb::CMs17191Specdb::CMs28718Specdb::CMs38884Specdb::CMs99876Specdb::CMs153745Specdb::MsMs50961Specdb::MsMs50962Specdb::MsMs50963Specdb::MsMs158097Specdb::MsMs158098Specdb::MsMs158099Specdb::MsMs449247Specdb::MsMs449248Specdb::MsMs449249Specdb::MsMs449250Specdb::MsMs449251Specdb::MsMs2235653Specdb::MsMs2237733Specdb::MsMs2237775Specdb::MsMs2239779Specdb::MsMs2239935Specdb::MsMs2362277Specdb::MsMs2362278Specdb::MsMs2362279Specdb::MsMs2600033Specdb::MsMs2600034Specdb::MsMs2600035HMDB05783CarawayType 1specificCarum carvi480320.00.00.0mg/100 gCeylon cinnamonType 1specificCinnamomum verum1286080.00.00.0mg/100 gClovesType 1specificSyzygium aromaticum2198680.00.00.0mg/100 gCuminType 1specificCuminum cyminum524620.00.00.0mg/100 gGingerType 1specificZingiber officinale94328187.300003187.300003052187.300003052mg/100 gHerbs and SpicesUnknowngenericNutmegType 1specificMyristica fragrans510890.00.00.0mg/100 gPepper (Spice)Type 1specificPiper nigrum132160.00.00.0mg/100 gStar aniseType 1specificIllicium verum1247780.00.00.0mg/100 gSweet bayType 1specificLaurus nobilis852230.00.00.0mg/100 gpungentamphitensive53analgesic56An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.anti 5-hydroxytryptamine73Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.anti aggregant94anti allergic103A drug used to treat allergic reactions.anti emetic253A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.anti hepatotoxic328Any compound that is able to prevent damage to the liver.anti histaminic331Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.anti inflammatory370A substance that reduces or suppresses inflammation.anti prostaglandin550A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.anti pyretic567A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.anti schistosomiac593A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.anti septic603A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.anti seratogenic605anti thromboxane651A substance that diminishes the rate of a chemical reaction.anti tussive674Any substance introduced into a living organism with therapeutic or diagnostic purpose.anti ulcer676One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.antioxidant502A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324.cancer preventive754A substance that inhibits or prevents the proliferation of neoplasms.cardiodepressant766A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.cardiotonic771A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.cholagogue800cyclooxygenase inhibitor849A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.depressor873fungicide940A substance used to destroy fungal pests.gastrostimulant949A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion.hepatoprotective981Any compound that is able to prevent damage to the liver.hypertensive1007hypotensive1021inotropic1037larvicide1063molluscicide1113A substance used to destroy pests of the phylum Mollusca.mutagenic1125nematicide1141A substance used to destroy pests of the phylum Nematoda (roundworms).pesticide1210Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.prostaglandin synthesis inhibitor1258A substance that diminishes the rate of a chemical reaction.sedative1311A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.thermogenic1355