| EI-MS/GC-MS | | Type | Description | Splash Key | View |
|---|
| Predicted GC-MS | Boldine, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | splash10-03ea-0193000000-4e9d104f3b9f63ebca85 | Spectrum | | Predicted GC-MS | Boldine, 2 TMS, Predicted GC-MS Spectrum - 70eV, Positive | splash10-0c29-1003900000-b3664d5a9866ae0e674e | Spectrum | | Predicted GC-MS | Boldine, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Boldine, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Boldine, TMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Boldine, TMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Boldine, TBDMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Boldine, TBDMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | | Predicted GC-MS | Boldine, TBDMS_2_1, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum |
|
|---|
| MS/MS | | Type | Description | Splash Key | View |
|---|
| MS/MS | LC-MS/MS Spectrum - LC-ESI-qTof , Positive | splash10-00kr-0590000000-f0be973ef3df7bed676d | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , negative | splash10-03di-0009000000-d2ba02385b9592588b92 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , positive | splash10-0002-0090000000-95c8c50b071b50db4c52 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - Linear Ion Trap , positive | splash10-000i-0009000000-34786ce337d46ea704b5 | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - , positive | splash10-00kr-0590000000-f0be973ef3df7bed676d | 2017-09-14 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-03dj-0097000000-67d87760a4caee6d5688 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0002-0090000000-e4cefc23c5dfb8ba6b98 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-002b-0960000000-fea69a015955b1a8c78a | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Negative | splash10-03xr-0096000000-eef48b135c01a8bce609 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-03fr-0009000000-ca3e6fc8ef8b4652939a | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-03di-0009000000-de5317cf2fdab8ede5f2 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-00or-0093000000-9ed026ef6b3924c14361 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-03dj-0189000000-74839a87c32b59674b9e | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-03xr-0096000000-7a5557a34d23c5435004 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-0002-0090000000-e2bcbd9b1e8cfe4b5c97 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-00or-0093000000-6425dc8e8623be8ff155 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-00kb-0090000000-0189a512fde7a38e7508 | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-00kb-0950000000-cfbc617d88a4d97d884b | 2021-09-20 | View Spectrum | | MS/MS | LC-MS/MS Spectrum - 6V, Positive | splash10-002b-0980000000-99aa3f6034bdf51f0c8f | 2021-09-20 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-004i-0019000000-1bf91ce02169cdc4f51b | 2015-04-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-004j-0097000000-f405b3e19193547c8a34 | 2015-04-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-017i-0090000000-a3de726762f74254538d | 2015-04-24 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-004i-0009000000-740d8346fca3f39b7095 | 2015-04-25 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-004i-0029000000-4fb006bf9d3d6f7f1138 | 2015-04-25 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-01qc-0091000000-090643282c4d4b487254 | 2015-04-25 | View Spectrum |
|
|---|
| Health Effects / Bioactivities | | Descriptor | ID | Definition | Reference |
|---|
| Abortifacient | 50691 | An agent that induces abortion, disrupting pregnancy by blocking progesterone or causing uterine contractions. Therapeutically, it's used to terminate early pregnancies, manage ectopic pregnancies, or treat miscarriages. Key medical uses include medical abortion, pregnancy termination, and menstrual regulation. | DUKE | | Anti-diabetic | 52217 | An agent that regulates blood sugar levels, enhancing insulin sensitivity or secretion. Therapeutically, it's used to manage diabetes, reducing symptoms and complications, and commonly prescribed to treat type 1 and 2 diabetes, as well as gestational diabetes. | DUKE | | Anti-edemic | | An agent that relieves or prevents edema, reducing abnormal fluid accumulation in tissues or the circulatory system, commonly used to treat conditions such as swelling, inflammation, and water retention. | DUKE | | Anti hepatotic | 62868 | An agent that protects the liver from damage, reducing inflammation and promoting liver health. It is used therapeutically to manage liver diseases, such as hepatitis and cirrhosis, and to prevent liver damage from toxins and medications. Key medical uses include treating liver conditions, supporting liver function, and preventing liver failure. | DUKE | | Anti-inflammatory | 35472 | An agent that reduces inflammation, playing a biological role in suppressing immune responses and therapeutic applications in managing pain, swelling, and redness. Key medical uses include treating arthritis, allergies, and autoimmune disorders, as well as relieving symptoms of conditions such as asthma and dermatitis. | DUKE | | Anti-lithic | | An agent that prevents the formation of calculi (kidney stones) or promotes their dissolution, playing a key role in urology. Its therapeutic applications include managing kidney stone disease, nephrolithiasis, and urinary tract disorders, helping to alleviate pain and prevent complications. | DUKE | | Anti-mutagenic | | An agent that interferes with the mutagenicity of a substance, preventing DNA damage and mutations. Its biological role is to protect cells from genetic alterations, and it has therapeutic applications in cancer prevention and treatment, as well as key medical uses in reducing the risk of genetic disorders and birth defects. | DUKE | | Anti-oxidant | 22586 | An agent that neutralizes free radicals, reducing oxidative stress and cell damage. Its biological role involves protecting cells from harm, and it has therapeutic applications in managing chronic diseases, such as cancer, diabetes, and neurodegenerative disorders, with key medical uses including anti-aging, anti-inflammatory, and cardio protective effects. | DUKE | | Anti prostaglandin | 49020 | An agent that inhibits prostaglandin production, reducing inflammation and pain. Therapeutically, it's used to treat conditions like arthritis, menstrual cramps, and post-surgical pain, by blocking prostaglandin-mediated responses, providing relief from inflammation and discomfort. | DUKE | | Anti pyretic | 35493 | An agent that reduces fever, commonly used to relieve headache, pain, and discomfort associated with elevated body temperature, and to manage fever in various medical conditions, such as infections and inflammatory diseases. | DUKE | | Anti radicular | | An agent that relieves inflammation or irritation of the nerve root of a tooth, reducing pain and discomfort. Its biological role is to target and alleviate radicular pain, with therapeutic applications in endodontics and key medical uses in root canal treatments and tooth sensitivity management. | DUKE | | Beta-adrenergic receptor blocker | 37962 | An agent that blocks beta-adrenergic receptors, reducing heart rate and blood pressure. Therapeutically, it manages hypertension, angina, and certain arrhythmias, while also being used to treat conditions like glaucoma, migraine headaches, and performance anxiety. | DUKE | | Calcium channel blocker | 38215 | An agent that blocks calcium ion influx, reducing muscle contraction and vascular resistance. Therapeutically, it lowers blood pressure, alleviates angina, and controls certain arrhythmias, commonly used in managing hypertension, coronary artery disease, and cardiac conditions. | DUKE | | Chemopreventive | 35610 | An agent that prevents or delays the development of cancer, reducing the risk of tumor formation and progression. It plays a biological role in inhibiting carcinogenesis, and has therapeutic applications in cancer prevention, with key medical uses including reducing the risk of colorectal, breast, and prostate cancers. | DUKE | | Choleretic | | An agent that increases bile production and secretion from the liver, enhancing digestion and fat absorption. Therapeutically, it's used to treat gallstones, liver disease, and indigestion, promoting healthy bile flow and liver function. | DUKE | | Convulsant | | An agent that induces convulsions and/or epileptic seizures, acting as a stimulant at low doses. It has no therapeutic applications due to its high risk of causing seizures and excitotoxicity, and is the opposite of an anticonvulsant. | DUKE | | Diuretic | 35498 | An agent that increases urine production, helping remove excess fluids and salts from the body. It plays a key biological role in regulating fluid balance and blood pressure. Therapeutically, diuretics are used to treat conditions such as hypertension, edema, and heart failure, helping reduce swelling and lower blood pressure. | DUKE | | Gastrostimulant | 55324 | An agent that stimulates digestive motility, increasing gastrointestinal movement and secretion. It enhances gut function, relieving symptoms of gastroparesis, constipation, and other motility disorders, commonly used in managing conditions like diabetes-related gastroparesis and postoperative ileus. | DUKE | | Hepatoprotective | 62868 | An agent that protects the liver from damage, promoting liver health and function. It plays a biological role in reducing oxidative stress and inflammation, and has therapeutic applications in managing liver diseases, such as hepatitis and cirrhosis, and key medical uses in treating drug-induced liver injury and toxicities. | DUKE | | Hydrogen-peroxide inhibitor | 35222 | An agent that blocks the harmful effects of hydrogen peroxide, reducing oxidative stress and inflammation. Therapeutically, it is used to manage conditions like cancer, neurodegenerative diseases, and cardiovascular disorders, protecting cells from damage and promoting overall health. | DUKE | | Hypnotic | | An agent that induces sleep, used to treat insomnia and facilitate surgical anesthesia, playing a key role in regulating sleep patterns and providing therapeutic relief for sleep disorders. | DUKE | | Immunomodulator | 50846 | An agent that regulates the immune system, modifying its response to maintain balance. Therapeutically, it's used to treat autoimmune diseases, prevent transplant rejection, and manage chronic inflammatory conditions, such as rheumatoid arthritis and multiple sclerosis. | DUKE | | Myorelaxant | | An agent that reduces muscle contractility by blocking nerve impulses or decreasing motor end plate excitability, used therapeutically to relieve muscle spasms, tension, and pain, commonly in managing musculoskeletal disorders, anxiety, and insomnia. | DUKE | | Neuroleptic | | An agent that reduces nervous tension by depressing nerve functions, primarily used to treat psychiatric disorders such as schizophrenia, anxiety, and agitation, and also used in managing symptoms of Tourette's syndrome and other neurological conditions. | DUKE | | Nitric-oxide inhibitor | 35222 | An agent that blocks the production of nitric oxide, reducing inflammation and vascular relaxation. Therapeutically, it's used to treat conditions like hypertension, angina, and septic shock, by constricting blood vessels and improving blood pressure. Key medical uses include cardiovascular and critical care applications. | DUKE | | Prostaglandin synthesis inhibitor | 35222 | An agent that blocks the production of prostaglandins, reducing inflammation and pain. Therapeutically, it's used to treat conditions like arthritis, menstrual cramps, and fever, commonly found in nonsteroidal anti-inflammatory drugs (NSAIDs). | DUKE | | Teratogenic | 50905 | An agent that causes abnormal fetal development, disrupting embryonic growth and leading to birth defects. Its biological role is associated with developmental toxicity, and it has no therapeutic applications. Key medical uses include serving as a warning for substances that pose risks during pregnancy, guiding prenatal care and medication management to prevent birth defects. | DUKE | | Uricosuric | | A substance that increases uric acid excretion in the urine, reducing blood plasma concentration. It plays a biological role in preventing uric acid buildup. Therapeutically, it's used to treat gout and hyperuricemia, managing symptoms and preventing complications. Key medical uses include reducing uric acid levels and alleviating gout attacks. | DUKE | | Vasoconstrictor | 50514 | An agent that narrows blood vessels, reducing blood flow. It plays a biological role in regulating blood pressure and is therapeutically used to treat conditions like hypotension, nasal congestion, and bleeding. Key medical uses include managing shock, reducing bleeding during surgery, and relieving migraine headaches. | DUKE |
|
|---|
