1.02010-04-08 22:05:56 UTC2019-11-26 02:59:33 UTCFDB003763ArsenicArsenic(As) is a ubiquitous metalloid found in several forms in food and the environment, such as the soil, air and water. Physiologically, it exists as an ion in the body. The predominant form is inorganic arsenic in drinking water, which is both highly toxic and carcinogenic and rapidly bioavailable. Arsenic is currently one of the most important environmental global contaminants and toxicants, particularly in the developing countries. For decades, very large populations have been and are currently still exposed to inorganic Arsenic through geogenically contaminated drinking water. An increased incidence of disease mediated by this toxicant is the consequence of long-term exposure. In human's chronic ingestion of inorganic arsenic (> 500 mg/L As) has been associated with cardiovascular, nervous, hepatic and renal diseases and diabetes mellitus as well as cancer of the skin, bladder, lung, liver and prostate. Contrary to the earlier view that methylated compounds are innocuous, the methylated metabolites are now recognized to be both toxic and carcinogenic, possibly due to genotoxicity, inhibition of antioxidative enzyme functions, or other mechanisms. Arsenic inhibits indirectly sulfhydryl containing enzymes and interferes with cellular metabolism. Effects involve such phenomena as cytotoxicity, genotoxicity and inhibition of enzymes with antioxidant function. These are all related to nutritional factors directly or indirectly. Nutritional studies both in experimental and epidemiological studies provide convincing evidence that nutritional intervention, including chemoprevention, offers a pragmatic approach to mitigate the health effects of arsenic exposure, particularly cancer, in the relatively resource-poor developing countries. Nutritional intervention, especially with micronutrients, many of which are antioxidants and share the same pathway with Arsenic , appears a host defence against the health effects of arsenic contamination in developing countries and should be embraced as it is pragmatic and inexpensive. (PMID: 17477765, 17179408)Agent saARSArsenArsenic [UN1558] [Poison]Arsenic and arsenic compoundsArsenic and certain arsenic compoundsArsenic and compoundsArsenic blackArsenic compoundsArsenic elementalArsenic hydrideArsenic hydride (AsH3)Arsenic trihydrideArsenic-75ARSENIC, 99.999%Arsenic, elementalArsenic, inorganicArsenic, Isotope Of Mass 72Arsenic, organic compoundsArsenic, water-soluble compounds, n.o.sArsenic, water-soluble compounds, n.o.s.ArsenicalsArsenicoArsenicumArsenicum Album 3ch-30ch GranulesArsenicum Iodatum 3ch-30chArseniuretted hydrogenArsenous hydrideArsenowodorArsineArsine [UN2188] [Poison gas]ASAs(3+)Colloidal arsenicCompounds, arsenicGray arsenicGrey arsenicHydrogen arsenideMetallic arsenicTrisenoxAsH377.945477.945071513arsanearsane7440-38-2[AsH3]InChI=1S/AsH3/h1H3RBFQJDQYXXHULB-UHFFFAOYSA-N belongs to the class of inorganic compounds known as trivalent inorganic arsenic compounds. These are inorganic compounds containing a trivalent arsenic atom.Trivalent inorganic arsenic compoundsInorganic compoundsMiscellaneous inorganic compoundsInorganic arsenic compoundsTrivalent inorganic arsenic compoundsMiscellaneous mixed metal/non-metalsMiscellaneous mixed metal/non-metalTrivalent inorganic arsenic compoundarsanesarsinemononuclear parent hydrideSolidmelting_point> 615 oClogp-0.23iupacarsaneaverage_mass77.9454mono_mass77.945071513smiles[AsH3]formulaAsH3inchiInChI=1S/AsH3/h1H3inchikeyRBFQJDQYXXHULB-UHFFFAOYSA-Npolar_surface_area0refractivity2.4polarizability3.4rotatable_bond_count0acceptor_count0donor_count0physiological_charge0formal_charge0Specdb::MsMs77061Specdb::MsMs77062Specdb::MsMs77063Specdb::MsMs137067Specdb::MsMs137068Specdb::MsMs137069HMDB0229027563#<Reference:0x0000555675a93140>#<Reference:0x0000555675a92f60>AlmondType 1specificPrunus dulcis37550.0020.0020.002mg/100 gAnatidaeType 1specificAnatidae8830AppleType 1specificMalus pumila2832100.021550.021550.02155mg/100 gAsparagusType 1specificAsparagus officinalis46860.000550.000550.00055mg/100 gBarleyType 1specificHordeum vulgare45130.0010.0010.001mg/100 gBeefaloType 1specificBos taurus X Bison bison297284BilberryType 1specificVaccinium myrtillus1807630.0010.0010.001mg/100 gBisonType 1specificBison bison9901Black walnutType 1specificJuglans nigra167190.0030.0030.003mg/100 gBlackcurrantType 1specificRibes nigrum785110.00350.00350.0035mg/100 gBrazil nutType 1specificBertholletia excelsa36450.0020.0020.002mg/100 gBroad beanType 1specificVicia faba39060.080.080.08mg/100 gBroccoliType 1specificBrassica oleracea var. italica367740.000450.00050.0004mg/100 gBuffaloType 1specificBubalus bubalis89462ButternutType 1specificJuglans cinerea912140.0020.0020.002mg/100 gCabbageType 1specificBrassica oleracea var. capitata37160.000550.000550.00055mg/100 gCarrotType 1specificDaucus carota ssp. sativus792000.0251750.050150.0002mg/100 gCashew nutType 1specificAnacardium occidentale1719290.0020.0020.002mg/100 gCattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031CloudberryType 1specificRubus chamaemorus57936CoconutType 1specificCocos nucifera138940.0020.0020.002mg/100 gColumbidae (Dove, Pigeon)Type 1specificColumbidae8930Common beanType 1specificPhaseolus vulgaris38850.0004250.000650.0002mg/100 gCommon grapeType 1specificVitis vinifera297600.04450.04450.0445mg/100 gCommon hazelnutType 1specificCorylus avellana134510.0020.0020.002mg/100 gCommon peaType 1specificPisum sativum38880.00250.00250.0025mg/100 gCommon salsifyType 1specificTragopogon porrifolius137310.0110.0110.011mg/100 gCommon wheatType 1specificTriticum aestivum45650.00790.00790.0079mg/100 gCornType 1specificZea mays45770.01060.01060.0106mg/100 gCow milk, pasteurized, vitamin A + D added, 0% fatType 2specificCow milk, pasteurized, vitamin A + D added, 1% fatType 2specificCow milk, pasteurized, vitamin A + D added, 2% fatType 2specificCow milk, pasteurized, vitamin D added, 3.25% fatType 2specificCucumberType 1specificCucumis sativus36590.0032080.012650.00003582mg/100 gDandelionType 1specificTaraxacum officinale50225DeerType 1specificCervidae9850DillType 1specificAnethum graveolens409220.002150.00350.0008mg/100 gDomestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825EggplantType 1specificSolanum melongena41110.000250.00040.0001mg/100 gElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790EndiveType 1specificCichorium endivia1142800.00440.00440.0044mg/100 gEuropean plumType 1specificPrunus domestica37580.025550.025550.02555mg/100 gEuropean rabbitType 1specificOryctolagus9984FlaxseedType 1specificLinum usitatissimum4006French plantainType 1specificMusa X paradisiaca89151Garden onionType 1specificAllium cepa46790.0014950.00390.000229106mg/100 gGarden rhubarbType 1specificRheum rhabarbarum36210.0010.0010.001mg/100 gGarden tomatoType 1specificSolanum lycopersicum40810.0000650.000080.00005mg/100 gGarden tomato (var.)Type 1specificSolanum lycopersicum var. lycopersicum3977550.00230.00230.0023mg/100 gGarlicType 1specificAllium sativum46820.002050.00260.0015mg/100 gGiant butterburType 1specificPetasites japonicus186965GooseberryType 1specificRibes uva-crispa135518Gram beanType 1specificVigna mungo39150.01620.01620.0162mg/100 gGreen bell pepperType 1specificCapsicum annuum40720.0005750.000950.0002mg/100 gGreen zucchiniType 1specificCucurbita pepo var. cylindrica0.0000880.0001017820.00007343mg/100 gGreylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796HorseradishType 1specificArmoracia rusticana37040.00250.00250.0025mg/100 gHyacinth beanType 1specificLablab purpureus359360.0020.0020.002mg/100 gIrish mossType 1specificChondrus crispus27691.01.01.0mg/100 gItalian sweet red pepperType 1specificCapsicum annuum40720.000040.000050.00003mg/100 gJapanese pumpkinType 1specificCucurbita maxima36610.000130.000150.00011mg/100 gLettuceType 1specificLactuca sativa42360.029050.029050.02905mg/100 gLoquatType 1specificEriobotrya japonica322240.0280.0280.028mg/100 gMallard duckType 1specificAnas platyrhynchos8839Mandarin orange (Clementine, Tangerine)Type 1specificCitrus reticulata855710.0170.0170.017mg/100 gMilk (Cow)Type 2specific0.0656240.4270.0003mg/100 gMountain hareType 1specificLepus timidus62621MugwortType 1specificArtemisia vulgaris4220Mule deerType 1specificOdocoileus9871Mung beanType 1specificVigna radiata1577910.0090.0090.009mg/100 gMuskmelonType 1specificCucumis melo36560.00050.00050.0005mg/100 gNutmegType 1specificMyristica fragrans510890.0010.0010.001mg/100 gOrange bell pepperType 1specificCapsicum annuum40720.0004010.000950.000123153mg/100 gOstrichType 1specificStruthio camelus8801ParsleyType 1specificPetroselinum crispum40430.0110.0110.011mg/100 gParsnipType 1specificPastinaca sativa40410.0005090.0010.000245128mg/100 gPeachType 1specificPrunus persica37600.00270.00270.0027mg/100 gPearType 1specificPyrus communis232110.003050.003050.00305mg/100 gPepperType 1specificCapsicum annuum40720.000950.000950.00095mg/100 gPheasantType 1specificPhasianus colchicus9054PistachioType 1specificPistacia vera555130.0020.0020.002mg/100 gPotatoType 1specificSolanum tuberosum41130.0101170.030050.0001mg/100 gQuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979RadishType 1specificRaphanus sativus3726Red beetrootType 1specificBeta vulgaris var. rubra0.0887380.350.00019mg/100 gRed bell pepperType 1specificCapsicum annuum40720.0003720.000950.00007567mg/100 gRedcurrantType 1specificRibes rubrum1752280.00950.00950.0095mg/100 gRiceType 1specificOryza sativa45300.02110.02110.0211mg/100 gRock ptarmiganType 1specificLagopus muta64668Romaine lettuceType 1specificLactuca sativa L. var. longifolia0.0001460.0001938080.0001mg/100 gSacred lotusType 1specificNelumbo nucifera44320.0110.0110.011mg/100 gSafflowerType 1specificCarthamus tinctorius42220.0480.0480.048mg/100 gSheep (Mutton, Lamb)Type 1specificOvis aries9940SpinachType 1specificSpinacia oleracea35620.0058330.01550.0009mg/100 gSquabType 1specificColumba8931Sunburst squash (pattypan squash)Type 1specificCucurbita pepo var. clypeata0.0001820.0002464970.0001mg/100 gSweet orangeType 1specificCitrus sinensis27110.007750.007750.00775mg/100 gTurkeyType 1specificMeleagris gallopavo9103TurnipType 1specificBrassica rapa var. rapa513500.0003050.000310.0003mg/100 gVelvet duckType 1specificMelanitta fusca371864White cabbageType 1specificBrassica oleracea L. var. capitata L. f. alba DC.0.0003250.000550.0001mg/100 gWhite mustardType 1specificSinapis alba37280.0050.0050.005mg/100 gWild boarType 1specificSus scrofa9823Wild carrotType 1specificDaucus carota40390.050150.050150.05015mg/100 gWild celeryType 1specificApium graveolens40450.0050.0050.005mg/100 gYellow bell pepperType 1specificCapsicum annuum40720.0003740.000950.00008299mg/100 gYellow zucchiniType 1specificCucurbita pepo var. cylindrica0.00020.00020.0002mg/100 gATPase ASNA1O43681ASNA1anorexic68An agent which regulates the physiologic mechanisms that control the appetite and food intake.pesticide1210Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.