1.02010-04-08 22:07:22 UTC2019-11-26 03:01:22 UTCFDB006932GenkwaninGenkwanin, also known as 5,4'-dihydroxy-7-methoxyflavone or 7-methylapigenin, is a member of the class of compounds known as 7-o-methylated flavonoids. 7-o-methylated flavonoids are flavonoids with methoxy groups attached to the C7 atom of the flavonoid backbone. Thus, genkwanin is considered to be a flavonoid lipid molecule. Genkwanin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Genkwanin is a bitter tasting compound and can be found in a number of food items such as winter savory, sweet basil, rosemary, and common sage, which makes genkwanin a potential biomarker for the consumption of these food products. Genkwanin is an O-methylated flavone, a type of flavonoid. It can be found in the seeds of Alnus glutinosa, and the leaves of the ferns Notholaena bryopoda and Asplenium normale .5,4'-Dihydroxy-7-methoxyflavone7-MethoxyapigeninApigenin 7-methyl etherFlavone, 4',5-dihydroxy-7-methoxy-GengkwaninC16H12O5284.2635284.0684734945-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-onegenkwanin437-64-9COC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=C(O)C=C1InChI=1S/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3JPMYFOBNRRGFNO-UHFFFAOYSA-N belongs to the class of organic compounds known as 7-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C7 atom of the flavonoid backbone.7-O-methylated flavonoidsOrganic compoundsPhenylpropanoids and polyketidesFlavonoidsO-methylated flavonoidsAromatic heteropolycyclic compounds1-hydroxy-2-unsubstituted benzenoids1-hydroxy-4-unsubstituted benzenoids4'-hydroxyflavonoids5-hydroxyflavonoidsAlkyl aryl ethersAnisolesBenzene and substituted derivativesChromonesFlavonesHeteroaromatic compoundsHydrocarbon derivativesOrganic oxidesOxacyclic compoundsPyranones and derivativesVinylogous acids1-benzopyran1-hydroxy-2-unsubstituted benzenoid1-hydroxy-4-unsubstituted benzenoid4'-hydroxyflavonoid5-hydroxyflavonoid7-methoxyflavonoid-skeletonAlkyl aryl etherAnisoleAromatic heteropolycyclic compoundBenzenoidBenzopyranChromoneEtherFlavoneHeteroaromatic compoundHydrocarbon derivativeHydroxyflavonoidMonocyclic benzene moietyOrganic oxideOrganic oxygen compoundOrganoheterocyclic compoundOrganooxygen compoundOxacyclePhenolPyranPyranoneVinylogous acidFlavones and FlavonolsFlavones and Flavonolsdihydroxyflavoneflavonesmonomethoxyflavonelogp3.39logs-3.71solubility5.59e-02 g/llogp2.85pka_strongest_acidic8.34pka_strongest_basic-4.7iupac5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-oneaverage_mass284.2635mono_mass284.068473494smilesCOC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=C(O)C=C1formulaC16H12O5inchiInChI=1S/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3inchikeyJPMYFOBNRRGFNO-UHFFFAOYSA-Npolar_surface_area75.99refractivity77.4polarizability28.87rotatable_bond_count2acceptor_count5donor_count2physiological_charge0formal_charge0Specdb::CMs114976Specdb::CMs129184Specdb::CMs893698Specdb::CMs893699Specdb::CMs893700Specdb::CMs893701Specdb::CMs893702Specdb::CMs893703Specdb::MsMs55707Specdb::MsMs55708Specdb::MsMs55709Specdb::MsMs110916Specdb::MsMs110917Specdb::MsMs110918Specdb::MsMs285700Specdb::MsMs285701Specdb::MsMs285702Specdb::MsMs285703Specdb::MsMs285704Specdb::MsMs2252260Specdb::MsMs2254218Specdb::MsMs2254299Specdb::MsMs2256275Specdb::MsMs3436106Specdb::MsMs3436107Specdb::MsMs3436108Specdb::MsMs3436109Specdb::MsMs3436110Common sageType 1specificSalvia officinalis38868Common thymeType 1specificThymus vulgaris49992RosemaryType 1specificRosmarinus officinalis39367Sweet basilType 1specificOcimum basilicum39350Winter savoryType 1specificSatureja montana49988bitteranti bacterial145A substance that kills or slows the growth of bacteria.pesticide1210Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.purgative1275An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic.