1.02010-04-08 22:10:15 UTC2020-09-17 15:42:23 UTCFDB012589DimethylamineDimethylamine, also known as DMA or (CH3)2NH, belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen. Dimethylamine is a very strong basic compound (based on its pKa). Dimethylamine (DMA) is also classified as a secondary amine. It is a colorless, liquefied and flammable gas with an ammonia and fish-like odor. Dimethylamine is abundantly present in human urine. The main sources of urinary DMA have been reported to include trimethylamine N-oxide, a common food component found in cold-water fish, and asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthesis. ADMA is excreted in the urine in part unmetabolized and in part after hydrolysis to DMA by dimethylarginine dimethylaminohydrolase (DDAH). Statistically significant increases in urinary DMA have been found in individuals after the consumption of fish and seafoods. The highest values were obtained for individuals that consumed coley, squid, whitting, cod, haddock, sardine, skate and swordfish (PMID: 18282650). DMA has also been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID: 22626821). Industrially, DMA is used as dehairing agent in tanning, in dyes, in rubber polymerization accelerators, in soaps and cleaning compounds and as an agricultural fungicide. In the body, DMA also undergoes nitrosation under weak acid conditions to give dimethlynitrosamine. Recent studies have shown that DMA is a metabolite produced by several species of bacteria including Arthrobacter and Micrococcus (PMID: 11422368). Dimethylamine is also found in cannabis smoke and is volatilized during the combustion of cannabis (https://doi.org/10.1007/978-1-59259-947-9_2).(CH3)2NHDimethylamine (anhydrous)Dimethylamine anhydrousDimethylamine anhydrous (dot)Dimethylamine aqueous solutionDimethylamine hydrobromideDimethylamine solutionDimethylamine, anhydrous [UN1032] [Flammable gas]Dimethylammonium bromideHNMe2Me2NHMethanamine, n-methyl-Methanamine, n-methyl-, hydrobromideN-methyl-methanamineN-methylmethanamineN-Methylmethanamine (acd/name 4.0)N-Methylmethanamine, 9CIN,n-dimethylaminenchem.125-comp12C2H7N45.083745.057849229dimethylaminedimethylamine124-40-3CNCInChI=1S/C2H7N/c1-3-2/h3H,1-2H3ROSDSFDQCJNGOL-UHFFFAOYSA-N belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.DialkylaminesOrganic compoundsOrganic nitrogen compoundsOrganonitrogen compoundsAminesAliphatic acyclic compoundsHydrocarbon derivativesOrganopnictogen compoundsAliphatic acyclic compoundHydrocarbon derivativeOrganopnictogen compoundSecondary aliphatic aminemethylaminessecondary aliphatic amineLiquidlogp-0.53logs1.06solubility5.16e+02 g/lmelting_pointMp -96°logp-0.19pka_strongest_basic10.52iupacdimethylamineaverage_mass45.0837mono_mass45.057849229smilesCNCformulaC2H7NinchiInChI=1S/C2H7N/c1-3-2/h3H,1-2H3inchikeyROSDSFDQCJNGOL-UHFFFAOYSA-Npolar_surface_area12.03refractivity14.69polarizability5.75rotatable_bond_count0acceptor_count1donor_count1physiological_charge1formal_charge0Specdb::NmrTwoD1135Specdb::EiMs899Specdb::MsIr162Specdb::MsIr163Specdb::MsIr164Specdb::CMs20008Specdb::CMs29401Specdb::CMs99533Specdb::CMs137140Specdb::CMs144874Specdb::NmrOneD1077Specdb::NmrOneD1138Specdb::NmrOneD142090Specdb::NmrOneD142091Specdb::NmrOneD142092Specdb::NmrOneD142093Specdb::NmrOneD142094Specdb::NmrOneD142095Specdb::NmrOneD142096Specdb::NmrOneD142097Specdb::NmrOneD142098Specdb::NmrOneD142099Specdb::NmrOneD142100Specdb::NmrOneD142101Specdb::NmrOneD142102Specdb::NmrOneD142103Specdb::NmrOneD142104Specdb::NmrOneD142105Specdb::NmrOneD142106Specdb::NmrOneD142107Specdb::NmrOneD142108Specdb::NmrOneD142109Specdb::NmrOneD166489Specdb::MsMs6123Specdb::MsMs6124Specdb::MsMs6125Specdb::MsMs6126Specdb::MsMs6127Specdb::MsMs6128Specdb::MsMs310543Specdb::MsMs310544Specdb::MsMs310545Specdb::MsMs355297Specdb::MsMs355298Specdb::MsMs355299Specdb::MsMs446053Specdb::MsMs446054Specdb::MsMs446055Specdb::MsMs446056Specdb::MsMs446057Specdb::MsMs2326977Specdb::MsMs2326978Specdb::MsMs2326979Specdb::MsMs2612029Specdb::MsMs2612030Specdb::MsMs2612031HMDB0008717170DMN#<Reference:0x00005556740e24d0>#<Reference:0x00005556740e1e40>#<Reference:0x00005556740e0e28>#<Reference:0x00005556740e0bd0>#<Reference:0x00005556740e04c8>#<Reference:0x00005556740e01a8>#<Reference:0x00005556740dff78>#<Reference:0x00005556740dfdc0>#<Reference:0x00005556740dfbe0>#<Reference:0x00005556740df9d8>#<Reference:0x00005556740df820>#<Reference:0x00005556740df668>#<Reference:0x00005556740df488>#<Reference:0x00005556740df280>#<Reference:0x00005556740df0c8>#<Reference:0x00005556740deee8>AnatidaeType 1specificAnatidae8830BarleyType 1specificHordeum vulgare45130.160.160.16mg/100 gBeefaloType 1specificBos taurus X Bison bison297284BeerType 2specific0.5750.5750.575mg/100 gBisonType 1specificBison bison9901BuffaloType 1specificBubalus bubalis89462CabbageType 1specificBrassica oleracea var. capitata37160.240.240.24mg/100 gCattle (Beef, Veal)Type 1specificBos taurus9913ChickenType 1specificGallus gallus9031Columbidae (Dove, Pigeon)Type 1specificColumbidae8930Common grapeType 1specificVitis vinifera29760CornType 1specificZea mays45770.230.230.23mg/100 gDeerType 1specificCervidae9850Domestic goatType 1specificCapra aegagrus hircus9925Domestic pigType 1specificSus scrofa domestica9825ElkType 1specificCervus canadensis1574408EmuType 1specificDromaius novaehollandiae8790European rabbitType 1specificOryctolagus9984French plantainType 1specificMusa X paradisiaca89151Grape wineType 2specific0.40.40.4mg/100 gGreylag gooseType 1specificAnser anser8843Guinea henType 1specificNumida meleagris8996HorseType 1specificEquus caballus9796Mallard duckType 1specificAnas platyrhynchos8839Milk (Cow)Type 2specific14.27857117.09.4uMMountain hareType 1specificLepus timidus62621Mule deerType 1specificOdocoileus9871OstrichType 1specificStruthio camelus8801PheasantType 1specificPhasianus colchicus9054QuailType 1specificPhasianidae9005RabbitType 1specificLeporidae9979RiceType 1specificOryza sativa4530Rock ptarmiganType 1specificLagopus muta64668Sheep (Mutton, Lamb)Type 1specificOvis aries9940Soy beanType 1specificGlycine max3847SquabType 1specificColumba8931TurkeyType 1specificMeleagris gallopavo9103Velvet duckType 1specificMelanitta fusca371864White cabbageType 1specificBrassica oleracea L. var. capitata L. f. alba DC.0.240.240.24mg/100 gWild boarType 1specificSus scrofa9823Wild celeryType 1specificApium graveolens4045N(G),N(G)-dimethylarginine dimethylaminohydrolase 2O95865DDAH2coleoptophile821pesticide1210Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.