Record Information |
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Version | 1.0 |
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Creation date | 2010-04-08 22:11:18 UTC |
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Update date | 2019-11-26 03:10:13 UTC |
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Primary ID | FDB014504 |
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Secondary Accession Numbers | Not Available |
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Chemical Information |
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FooDB Name | Folic acid |
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Description | Folic acid, also known as folate or folsaeure, belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Folic acid is a moderately basic compound (based on its pKa). Folic acid exists in all living species, ranging from bacteria to humans. Folic acid is a potentially toxic compound. Folic acid, with regard to humans, has been found to be associated with several diseases such as fibromyalgia, hereditary folate malabsorption, bladder infections, and alzheimer's disease; folic acid has also been linked to the inborn metabolic disorder folate deficiency. |
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CAS Number | 59-30-3 |
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Structure | |
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Synonyms | Synonym | Source |
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Folate | ChEBI | Folsaeure | ChEBI | N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid | ChEBI | N-Pteroyl-L-glutamic acid | ChEBI | PGA | ChEBI | PteGlu | ChEBI | Pteroyl-L-glutamic acid | ChEBI | Pteroyl-L-monoglutamic acid | ChEBI | Pteroylglutamic acid | ChEBI | Vitamin BC | ChEBI | Vitamin m | ChEBI | Folicet | Kegg | N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamate | Generator | N-Pteroyl-L-glutamate | Generator | Pteroyl-L-glutamate | Generator | Pteroyl-L-monoglutamate | Generator | Pteroylglutamate | Generator | Acifolic | HMDB | Cytofol | HMDB | Dosfolat b activ | HMDB | Folacid | HMDB | Folacin | HMDB | Folbal | HMDB | Folcidin | HMDB | Foldine | HMDB | Folettes | HMDB | Foliamin | HMDB | Folipac | HMDB | Folsan | HMDB | Folsaure | HMDB | Folsav | HMDB | Folvite | HMDB | Incafolic | HMDB | Liver lactobacillus casei factor | HMDB | Millafol | HMDB | N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid | HMDB | N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid | HMDB | Pteroylmonoglutamic acid | HMDB | Vitamin be | HMDB | Folic acid, (DL)-isomer | HMDB | Folic acid, sodium salt | HMDB | Folic acid, (D)-isomer | HMDB | Folic acid, monosodium salt | HMDB | Folic acid, potassium salt | HMDB | b9, Vitamin | HMDB | Folic acid, calcium salt (1:1) | HMDB | Folic acid, monopotassium salt | HMDB | Vitamin b9 | HMDB | Citrovorin | db_source | Coenzyme F | db_source | Factor u | biospider | Folcysteine | biospider | Folic acid | biospider | Foluite | biospider | Folvron | biospider | Leucal | db_source | Mittafol | biospider | N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]glutamic acid, 9CI | db_source | N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-Pteridinyl)methyl]amino]benzoyl]-L-glutamic acid | HMDB | Pteroylmonoglutamate | biospider | Vitamin b | biospider | Vitamin B11 | biospider | Vitamin B9 | biospider | Vitamin Bc | db_source | Vitamin M | db_source |
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Predicted Properties | |
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Chemical Formula | C19H19N7O6 |
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IUPAC name | (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid |
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InChI Identifier | InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1 |
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InChI Key | OVBPIULPVIDEAO-LBPRGKRZSA-N |
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Isomeric SMILES | NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1 |
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Average Molecular Weight | 441.3975 |
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Monoisotopic Molecular Weight | 441.139681375 |
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Classification |
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Description | Belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. |
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Kingdom | Organic compounds |
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Super Class | Benzenoids |
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Class | Phenols |
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Sub Class | Methoxyphenols |
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Direct Parent | Methoxyphenols |
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Alternative Parents | |
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Substituents | - Methoxyphenol
- Phenoxy compound
- Anisole
- Methoxybenzene
- Phenol ether
- 1-hydroxy-2-unsubstituted benzenoid
- Alkyl aryl ether
- Monocyclic benzene moiety
- Carboxylic acid derivative
- Monocarboxylic acid or derivatives
- Ether
- Carboxylic acid
- Organic oxygen compound
- Organooxygen compound
- Carbonyl group
- Hydrocarbon derivative
- Organic oxide
- Aromatic homomonocyclic compound
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Molecular Framework | Aromatic homomonocyclic compounds |
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External Descriptors | |
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Ontology |
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Physiological effect | Health effect: |
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Disposition | Route of exposure: Source: Biological location: |
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Process | Naturally occurring process: |
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Role | Industrial application: Biological role: |
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Physico-Chemical Properties |
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Physico-Chemical Properties - Experimental | Property | Value | Reference |
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Physical state | Solid | |
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Physical Description | Not Available | |
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Mass Composition | C 51.70%; H 4.34%; N 22.21%; O 21.75% | DFC |
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Melting Point | 250 oC | |
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Boiling Point | Not Available | |
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Experimental Water Solubility | 0.0016 mg/mL at 25 oC | MERCK INDEX (1983) |
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Experimental logP | Not Available | |
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Experimental pKa | Not Available | |
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Isoelectric point | Not Available | |
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Charge | Not Available | |
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Optical Rotation | [a]25D +23 (c, 0.5 in 1M NaOH) | DFC |
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Spectroscopic UV Data | Not Available | |
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Density | Not Available | |
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Refractive Index | Not Available | |
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Spectra |
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Spectra | |
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EI-MS/GC-MS | Type | Description | Splash Key | View |
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EI-MS | Mass Spectrum (Electron Ionization) | splash10-0006-9410000000-7cba521e870757539424 | 2014-09-20 | View Spectrum | Predicted GC-MS | Folic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | splash10-0002-2249100000-5ad16461f6638538ea08 | Spectrum | Predicted GC-MS | Folic acid, 2 TMS, Predicted GC-MS Spectrum - 70eV, Positive | splash10-00xr-4205390000-4152e24c68306bfe6554 | Spectrum | Predicted GC-MS | Folic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_1_3, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_1_4, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_1_5, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_1_6, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_2, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_3, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_4, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_5, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_6, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_7, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_8, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_9, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_10, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_11, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_12, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_13, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_14, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_15, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TMS_2_16, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Folic acid, TBDMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum |
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MS/MS | Type | Description | Splash Key | View |
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MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated) | splash10-0006-0000900000-4208ea3c2f5d9026c19f | 2012-07-24 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated) | splash10-0006-0050900000-2c8ad037dc3b270765c4 | 2012-07-24 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated) | splash10-0007-0090300000-ebdec84cbb7fe5afbc0b | 2012-07-24 | View Spectrum | MS/MS | LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negative | splash10-0007-0903600000-e5d91e4f2ab79d130b76 | 2012-08-31 | View Spectrum | MS/MS | LC-MS/MS Spectrum - LC-ESI-qTof , Positive | splash10-002b-0960000000-108d96993dc78f1e4b61 | 2017-09-14 | View Spectrum | MS/MS | LC-MS/MS Spectrum - LC-ESI-QTOF , negative | splash10-0007-0903600000-e5d91e4f2ab79d130b76 | 2017-09-14 | View Spectrum | MS/MS | LC-MS/MS Spectrum - , positive | splash10-002b-0960000000-108d96993dc78f1e4b61 | 2017-09-14 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 10V, Positive | splash10-0002-0090000000-9e9a33bc590d0f801929 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 30V, Positive | splash10-0aba-6940000000-f0b6076af9cb59413656 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 0V, Positive | splash10-0005-0090600010-5ef6e95b870cc0ebfeb8 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 20V, Positive | splash10-0002-0190000000-2d1f624dc1d2d929527f | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 90V, Negative | splash10-015c-9700000000-5a0aeec6b1c2bfddfdf1 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 10V, Positive | splash10-0002-0090000000-b750c262ac740994e33a | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 0V, Positive | splash10-0005-0090600000-c0e3753ba3591c41d1db | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 75V, Negative | splash10-001i-3900000000-4d5187e4336ce6be5eb7 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 40V, Positive | splash10-00b9-0910000000-b3bc3e8ccbba45c85e78 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 10V, Positive | splash10-0002-0090000010-2c53d9aa251e75638183 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 10V, Negative | splash10-0006-0000900000-7370828adb963cbb9246 | 2021-09-20 | View Spectrum | MS/MS | LC-MS/MS Spectrum - 20V, Negative | splash10-0006-0000900000-3b979cd5ecd30ae0d2bf | 2021-09-20 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-00bd-0544900000-aa9a130e2cf3dacfb954 | 2016-09-14 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-004j-0954100000-7be7eac442233b5d3bcf | 2016-09-14 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-004i-1960000000-1950169762886f41b6ec | 2016-09-14 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0006-0114900000-bff7f5f3d20dcd6a4494 | 2016-09-14 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-00r7-1249300000-e322ba8675bb922877a9 | 2016-09-14 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-9652000000-8c87fa7172ed19a7eb27 | 2016-09-14 | View Spectrum |
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NMR | Type | Description | | View |
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1D NMR | 1H NMR Spectrum (1D, 500 MHz, H2O, experimental) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 400 MHz, DMSO-d6, experimental) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 22.53 MHz, DMSO-d6, experimental) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, D2O, experimental) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, D2O, experimental) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 100 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 100 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 200 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 200 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 300 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 300 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 400 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 400 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 500 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 500 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 600 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 600 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 700 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 700 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 800 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 800 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 900 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 900 MHz, D2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 1000 MHz, D2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, D2O, predicted) | | Spectrum | 2D NMR | [1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, H2O, experimental) | | Spectrum |
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External Links |
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ChemSpider ID | 5815 |
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ChEMBL ID | CHEMBL1622 |
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KEGG Compound ID | C00504 |
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Pubchem Compound ID | 6037 |
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Pubchem Substance ID | Not Available |
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ChEBI ID | 27470 |
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Phenol-Explorer ID | Not Available |
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DrugBank ID | DB00158 |
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HMDB ID | HMDB00121 |
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CRC / DFC (Dictionary of Food Compounds) ID | JRL93-O:JRL93-O |
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EAFUS ID | 1396 |
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Dr. Duke ID | FOLIC-ACID|FOLACIN|FOLATE |
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BIGG ID | 35180 |
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KNApSAcK ID | C00001539 |
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HET ID | FOL |
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Food Biomarker Ontology | Not Available |
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VMH ID | Not Available |
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Flavornet ID | Not Available |
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GoodScent ID | rw1098971 |
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SuperScent ID | Not Available |
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Wikipedia ID | Folic acid |
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Phenol-Explorer Metabolite ID | Not Available |
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Duplicate IDS | Not Available |
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Old DFC IDS | Not Available |
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Associated Foods |
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Food | Content Range | Average | Reference |
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Food | | | Reference |
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Biological Effects and Interactions |
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Health Effects / Bioactivities | Descriptor | ID | Definition | Reference |
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Anti-anemic | 52217 | An agent that treats or prevents anemia by increasing red blood cell production or enhancing iron utilization, commonly used to manage iron-deficiency anemia, vitamin deficiency anemia, and other blood disorders, promoting healthy oxygen delivery to tissues and organs. | DUKE | Anti-cervicaldysplasic | 52217 | An agent that prevents or treats cervical dysplasia, a precancerous condition. It helps maintain normal cell growth, reducing the risk of cervical cancer. Therapeutically, it is used to manage abnormal cell changes in the cervix, often caused by HPV infection, and is a key component in cervical cancer prevention and treatment strategies. | DUKE | Anti cheilitic | | An agent that treats cheilitis, reducing inflammation and discomfort. Examples include corticosteroids and anti-inflammatory agents, commonly used to manage cheilitis symptoms and promote healing. | DUKE | Anti coronary | 52217 | An agent that reduces the risk of coronary artery disease, lowering blood pressure and cholesterol levels. It helps prevent heart attacks, strokes, and other cardiovascular events, commonly used in managing hypertension, hyperlipidemia, and atherosclerosis. | DUKE | Anti-dementia | 52217 | An agent that slows or prevents cognitive decline, reducing symptoms of dementia. It plays a biological role in neuroprotection, enhancing neuronal function and survival. Therapeutically, it is used to manage Alzheimer's disease, vascular dementia, and other neurodegenerative disorders, improving memory, cognition, and daily functioning. | DUKE | Anti depressant | 52217 | An agent that regulates mood, reducing symptoms of depression and anxiety by altering neurotransmitter levels in the brain, commonly used in managing depression, anxiety disorders, and other mood disorders. | DUKE | Anti-gingivitic | 52217 | An agent that reduces gingivitis symptoms, commonly used in managing plaque, inflammation, and gum disease, promoting oral health by preventing bacterial growth and infection. | DUKE | Anti-glossitic | | An agent that relieves inflammation of the tongue, or glossitis, playing a role in reducing pain and discomfort. Therapeutically, it is used to treat tongue inflammation, often caused by nutritional deficiencies or infections. Key medical uses include managing glossitis symptoms, promoting oral health, and improving quality of life for patients with tongue inflammation. | DUKE | Anti-gout | 52217 | An agent that reduces uric acid levels, used to treat and prevent gout attacks, managing symptoms such as joint pain and inflammation, and commonly prescribed for hyperuricemia and chronic gout management. | DUKE | Anti-infertility | 52217 | An agent that enhances reproductive health, promoting fertility and conception. Its biological role involves regulating hormonal balance and improving reproductive function. Therapeutically, it is used to treat infertility disorders, with key medical applications in assisted reproduction, polycystic ovary syndrome (PCOS), and unexplained infertility. | DUKE | Anti metaplastic | | An antibody targeting metaplastic carcinoma of the breast, playing a role in cancer treatment. Its therapeutic application involves inhibiting tumor growth and metastasis. Key medical uses include treating metaplastic breast cancer, a rare and aggressive subtype, offering a potential therapeutic option for patients with limited treatment choices. | DUKE | Anti myelotoxic | 50247 | An agent that protects the bone marrow from damage, reducing the toxic effects of chemotherapy and radiation on blood cell production, commonly used to support cancer treatment and manage related side effects. | DUKE | Anti neuropathic | | An agent that relieves symptoms such as pain, numbness, and tingling caused by damage or disease affecting the somatosensory nervous system, commonly used in managing conditions like diabetes, shingles, and nerve injuries. | DUKE | Anti periodontal | | An agent that prevents or treats gum disease, reducing inflammation and infection in the gums and supporting tissues of the teeth, commonly used in managing periodontitis and promoting oral health. | DUKE | Anti periodontitic | | An agent that reduces inflammation of tissue around teeth, preventing gum shrinkage and tooth loosening, commonly used to treat periodontal disease and promote oral health. | DUKE | Anti-plaque | | An agent that removes or prevents the formation of dental plaque, a biofilm of bacteria, to prevent tooth decay and gum disease, commonly used in oral care products and therapeutic applications for periodontal health. | DUKE | Anti polyp | | An agent that removes or prevents overgrowth of the inner wall of the colon or rectum, playing a role in colon health. Therapeutically, it helps prevent colorectal polyps, reducing the risk of colorectal cancer. Key medical uses include preventing polyp recurrence and managing conditions like familial adenomatous polyposis. | DUKE | Anti psychotic | 35476 | An agent that reduces psychotic symptoms, commonly used in managing schizophrenia, bipolar disorder, and other mental health conditions by blocking dopamine receptors in the brain, thereby alleviating hallucinations, delusions, and disordered thinking. | DUKE | Anti spina-bifida | 52217 | An agent that prevents or reduces the occurrence of spina bifida, a birth defect where the spine and spinal cord don't form properly. Its biological role is to promote proper neural tube formation. Therapeutically, it's used to prevent birth defects, particularly in high-risk pregnancies. Key medical uses include prenatal care and fetal development support, often involving folic acid supplementation. | DUKE | Cancer preventive | 35610 | An agent that inhibits the development and progression of cancer, reducing tumor formation and growth. It plays a biological role in blocking carcinogenic pathways, and has therapeutic applications in chemoprevention. Key medical uses include reducing the risk of cancer in high-risk individuals and preventing cancer recurrence. | DUKE | Hematopoietic | | An agent that stimulates the production of all types of blood cells, playing a crucial role in hematopoiesis. Therapeutically, it is used to treat blood disorders, such as anemia, and to support recovery after chemotherapy or bone marrow transplantation, promoting healthy blood cell production. | DUKE | Immunostimulant | 50847 | An agent that stimulates the immune system, enhancing its response to infections and diseases. Therapeutically, it boosts the body's natural defenses, commonly used to treat immunodeficiency disorders, prevent infections, and support cancer treatment, as well as manage chronic conditions like hepatitis and HIV. | DUKE | Uricosuric | | A substance that increases uric acid excretion in the urine, reducing blood plasma concentration. It plays a biological role in preventing uric acid buildup. Therapeutically, it's used to treat gout and hyperuricemia, managing symptoms and preventing complications. Key medical uses include reducing uric acid levels and alleviating gout attacks. | DUKE | Xanthine oxidase inhibitor | 35634 | An agent that blocks xanthine oxidase, an enzyme involved in uric acid production, reducing inflammation and oxidative stress. Therapeutically, it's used to treat gout, hyperuricemia, and prevent kidney stones, with key applications in managing cardiovascular disease and improving kidney function. | DUKE |
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Enzymes | Name | Gene Name | UniProt ID |
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Formimidoyltransferase-cyclodeaminase | FTCD | O95954 | Thiamine transporter 1 | SLC19A2 | O60779 | Dihydrofolate reductase | DHFR | P00374 | Folate receptor alpha | FOLR1 | P15328 | Folate transporter 1 | SLC19A1 | P41440 | Folate receptor gamma | FOLR3 | P41439 | Gamma-glutamyl hydrolase | GGH | Q92820 |
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Pathways | |
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Metabolism | Not Available |
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Biosynthesis | Not Available |
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Organoleptic Properties |
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Flavours | Flavor | Citations |
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odorless |
- The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
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Files |
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MSDS | show |
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References |
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Synthesis Reference | Not Available |
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General Reference | Not Available |
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Content Reference | — Saxholt, E., et al. 'Danish food composition databank, revision 7.' Department of Nutrition, National Food Institute, Technical University of Denmark (2008). — U.S. Department of Agriculture, Agricultural Research Service. 2008. USDA National Nutrient Database for Standard Reference, Release 21. Nutrient Data Laboratory Home Page. — Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004). — Shinbo, Y., et al. 'KNApSAcK: a comprehensive species-metabolite relationship database.' Plant Metabolomics. Springer Berlin Heidelberg, 2006. 165-181.
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