1.0 2011-09-21 00:28:13 UTC 2025-11-19 02:43:47 UTC FDB023331 N1-Methyl-4-pyridone-3-carboxamide N1-Methyl-4-pyridone-5-carboxamide (4PY ) is a normal human metabolite (one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation). 4PY concentration in serum is elevated in non-dialyzed chronic renal failure (CRF) patients when compared with controls. (PMID 12694300) [HMDB] 1-Methyl-4-oxo-1,4-dihydro-3-pyridinecarboxamide 1-Methyl-4-pyridone-3-carboxamide 1-Methyl-4-pyridone-3-carboximide 1-Methyl-4-pyridone-5-carboxamide 1,4-dihydro-1-Methyl-4-oxo-3-pyridinecarboxamide 3-(Aminocarbonyl)-1-methyl-4(1H)-pyridone 5-Aminocarbonyl-1-methyl-4(1H)-pyridone N'-Methyl-4-pyridone-5-carboxamide N1-Methyl-4-pyridone-3-carboxamide N1-Methyl-4-pyridone-5-carboxamide C7H8N2O2 152.1506 152.05857751 1-methyl-4-oxo-1,4-dihydropyridine-3-carboxamide 1-methyl-4-oxopyridine-3-carboxamide 769-49-3 CN1C=CC(=O)C(=C1)C(N)=O InChI=1S/C7H8N2O2/c1-9-3-2-6(10)5(4-9)7(8)11/h2-4H,1H3,(H2,8,11) KTLRWTOPTKGYQY-UHFFFAOYSA-N belongs to the class of organic compounds known as nicotinamides. These are heterocyclic aromatic compounds containing a pyridine ring substituted at position 3 by a carboxamide group. Nicotinamides Organic compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Aromatic heteromonocyclic compounds Azacyclic compounds Cyclic ketones Dihydropyridines Heteroaromatic compounds Hydrocarbon derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Primary carboxylic acid amides Vinylogous amides Aromatic heteromonocyclic compound Azacycle Carboxamide group Carboxylic acid derivative Cyclic ketone Dihydropyridine Heteroaromatic compound Hydrocarbon derivative Hydropyridine Nicotinamide Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary carboxylic acid amide Vinylogous amide methylpyridines pyridinecarboxamide pyridone Solid logp -1.02 ALOGPS logs -0.12 ALOGPS solubility 1.15e+02 g/l ALOGPS logp -0.56 ChemAxon pka_strongest_acidic 15.73 ChemAxon pka_strongest_basic 0.39 ChemAxon iupac 1-methyl-4-oxo-1,4-dihydropyridine-3-carboxamide ChemAxon average_mass 152.1506 ChemAxon mono_mass 152.05857751 ChemAxon smiles CN1C=CC(=O)C(=C1)C(N)=O ChemAxon formula C7H8N2O2 ChemAxon inchi InChI=1S/C7H8N2O2/c1-9-3-2-6(10)5(4-9)7(8)11/h2-4H,1H3,(H2,8,11) ChemAxon inchikey KTLRWTOPTKGYQY-UHFFFAOYSA-N ChemAxon polar_surface_area 63.4 ChemAxon refractivity 40.81 ChemAxon polarizability 14.7 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Nicotinate and Nicotinamide Metabolism SMP00048 map00760 Specdb::CMs 14640 Specdb::CMs 146006 Specdb::MsIr 2161 Specdb::MsIr 2162 Specdb::MsIr 2163 Specdb::NmrOneD 41842 Specdb::NmrOneD 41843 Specdb::NmrOneD 41844 Specdb::NmrOneD 41845 Specdb::NmrOneD 41846 Specdb::NmrOneD 41847 Specdb::NmrOneD 41848 Specdb::NmrOneD 41849 Specdb::NmrOneD 41850 Specdb::NmrOneD 41851 Specdb::NmrOneD 41852 Specdb::NmrOneD 41853 Specdb::NmrOneD 41854 Specdb::NmrOneD 41855 Specdb::NmrOneD 41856 Specdb::NmrOneD 41857 Specdb::NmrOneD 41858 Specdb::NmrOneD 41859 Specdb::NmrOneD 41860 Specdb::NmrOneD 41861 Specdb::MsMs 68313 Specdb::MsMs 68314 Specdb::MsMs 68315 Specdb::MsMs 126315 Specdb::MsMs 126316 Specdb::MsMs 126317 Specdb::MsMs 2227039 Specdb::MsMs 2227690 Specdb::MsMs 2229371 Specdb::MsMs 2230080 Specdb::MsMs 2231679 Specdb::MsMs 2232526 Specdb::MsMs 2234086 Specdb::MsMs 2234835 Specdb::MsMs 2254980 Specdb::MsMs 2255620 Specdb::MsMs 2364577 Specdb::MsMs 2364578 Specdb::MsMs 2364579 Specdb::MsMs 2597275 Specdb::MsMs 2597276 Specdb::MsMs 2597277 HMDB04194 #<Reference:0x000055ce3181d1e8> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823