1.0 2011-09-21 01:49:49 UTC 2015-07-21 06:59:37 UTC FDB029079 (-)-Salsoline (-)-Salsoline is a compound that crystallizes from alcohol solution, melts at 221 oC, soluble in hot alcohol and chloroform; used in medicine as an antihypertensive agent. Salsoline as well as salsolinol were found in male alcoholic inpatients's urine and lumbar cerebrospinal fluid when patients were still intoxicated after a heavy alcohol debauch and after they had been inpatients and off alcohol for one week.There was a wide interindividual variation and no statistical significant difference in the levels between the first and second sampling in CSF or urine.[PMID: 6935920] [HMDB] (1S)-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol Salsoline C11H15NO2 193.2423 193.110278729 (1S)-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol salsoline 89-31-6 COC1=CC2=C(CCN[C@H]2C)C=C1O InChI=1S/C11H15NO2/c1-7-9-6-11(14-2)10(13)5-8(9)3-4-12-7/h5-7,12-13H,3-4H2,1-2H3/t7-/m0/s1 YTPRLBGPGZHUPD-ZETCQYMHSA-N belongs to the class of organic compounds known as tetrahydroisoquinolines. These are tetrahydrogenated isoquinoline derivatives. Tetrahydroisoquinolines Organic compounds Organoheterocyclic compounds Tetrahydroisoquinolines Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids Alkyl aryl ethers Anisoles Aralkylamines Azacyclic compounds Dialkylamines Hydrocarbon derivatives Organopnictogen compounds 1-hydroxy-2-unsubstituted benzenoid Alkyl aryl ether Amine Anisole Aralkylamine Aromatic heteropolycyclic compound Azacycle Benzenoid Ether Hydrocarbon derivative Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Secondary aliphatic amine Secondary amine Tetrahydroisoquinoline isoquinolines Solid logp 0.92 ALOGPS logs -1.89 ALOGPS solubility 2.51e+00 g/l ALOGPS logp 1.14 ChemAxon pka_strongest_acidic 10.1 ChemAxon pka_strongest_basic 9.07 ChemAxon iupac (1S)-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol ChemAxon average_mass 193.2423 ChemAxon mono_mass 193.110278729 ChemAxon smiles COC1=CC2=C(CCN[C@H]2C)C=C1O ChemAxon formula C11H15NO2 ChemAxon inchi InChI=1S/C11H15NO2/c1-7-9-6-11(14-2)10(13)5-8(9)3-4-12-7/h5-7,12-13H,3-4H2,1-2H3/t7-/m0/s1 ChemAxon inchikey YTPRLBGPGZHUPD-ZETCQYMHSA-N ChemAxon polar_surface_area 41.49 ChemAxon refractivity 55.48 ChemAxon polarizability 21.3 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 12776 Specdb::CMs 39927 Specdb::CMs 163656 Specdb::MsIr 2768 Specdb::MsIr 2769 Specdb::MsIr 2770 Specdb::NmrOneD 97378 Specdb::NmrOneD 97379 Specdb::NmrOneD 97380 Specdb::NmrOneD 97381 Specdb::NmrOneD 97382 Specdb::NmrOneD 97383 Specdb::NmrOneD 97384 Specdb::NmrOneD 97385 Specdb::NmrOneD 97386 Specdb::NmrOneD 97387 Specdb::NmrOneD 97388 Specdb::NmrOneD 97389 Specdb::NmrOneD 97390 Specdb::NmrOneD 97391 Specdb::NmrOneD 97392 Specdb::NmrOneD 97393 Specdb::NmrOneD 97394 Specdb::NmrOneD 97395 Specdb::NmrOneD 97396 Specdb::NmrOneD 97397 Specdb::MsMs 294046 Specdb::MsMs 294047 Specdb::MsMs 294048 Specdb::MsMs 334669 Specdb::MsMs 334670 Specdb::MsMs 334671 Specdb::MsMs 2378383 Specdb::MsMs 2378384 Specdb::MsMs 2378385 Specdb::MsMs 2557446 Specdb::MsMs 2557447 Specdb::MsMs 2557448 HMDB12469 #<Reference:0x000055ce2ca1b850>