1.0 2026-09-22 04:35:53 UTC 2026-09-22 04:35:53 UTC FDB117712 Alovudine 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione C10H13FN2O4 244.222 244.08593507 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-5-methyl-1,2-dihydropyrimidin-2-one alovudine [H][C@]1(F)C[C@@]([H])(O[C@]1([H])CO)N1C=C(C)C(O)=NC1=O InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1 UXCAQJAQSWSNPQ-XLPZGREQSA-N belongs to the class of organic compounds known as pyrimidine 2',3'-dideoxyribonucleosides. Pyrimidine 2',3'-dideoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at positions 2 and 3. Pyrimidine 2',3'-dideoxyribonucleosides Organic compounds Nucleosides, nucleotides, and analogues Pyrimidine nucleosides Pyrimidine 2',3'-dideoxyribonucleosides Aromatic heteromonocyclic compounds Alkyl fluorides Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Lactams Organic oxides Organofluorides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Primary alcohols Pyrimidones Tetrahydrofurans Ureas Vinylogous amides Alcohol Alkyl fluoride Alkyl halide Aromatic heteromonocyclic compound Azacycle Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Lactam Organic nitrogen compound Organic oxide Organic oxygen compound Organofluoride Organohalogen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Primary alcohol Pyrimidine Pyrimidine 2',3'-dideoxyribonucleoside Pyrimidone Tetrahydrofuran Urea Vinylogous amide logp -0.78 ALOGPS logs -1.80 ALOGPS solubility 3.90e+00 g/l ALOGPS logp 0.14 ChemAxon pka_strongest_acidic 7.36 ChemAxon pka_strongest_basic -3 ChemAxon iupac 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-5-methyl-1,2-dihydropyrimidin-2-one ChemAxon average_mass 244.222 ChemAxon mono_mass 244.08593507 ChemAxon smiles [H][C@]1(F)C[C@@]([H])(O[C@]1([H])CO)N1C=C(C)C(O)=NC1=O ChemAxon formula C10H13FN2O4 ChemAxon inchi InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1 ChemAxon inchikey UXCAQJAQSWSNPQ-XLPZGREQSA-N ChemAxon polar_surface_area 82.36 ChemAxon refractivity 54.04 ChemAxon polarizability 22.04 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 5 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 80082 Specdb::MsMs 80083 Specdb::MsMs 80084 Specdb::MsMs 140838 Specdb::MsMs 140839 Specdb::MsMs 140840